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  • 4.9 reviews

    Liposomal Vitamin B12 + B6 (28)

    Supports natural detoxification

    Save 20% today

    30-day supply delivered monthly. Pause, skip or cancel anytime.

    Best Value

    Renews until you cancel. Pause, skip or cancel anytime.

    60-Day money back guarantee

    Made with care. Verified for quality.

    Certifications and standards selected for Liposomal Vitamin B12 + B6 (28).

    • Clean Label Project Certified Clean Label Project Certified
    • Clean Label Project Purity Award Clean Label Project Purity Award

    Product standards

    • GMP Certified
    • Non-GMO
    • No Artificial Flavors
    • No Preservatives
    • Plant Based
    • Gluten Free
    • Soy Free
    • Keto
    • Third Party Tested
    • Made In USA
    Results You Can Feel

    Results You Can Feel

    Brain Health*

    Bioavailable B vitamins help maintain cognitive function, mental clarity, and healthy neurological function.*

    Heart Health*

    P5P and methylated folate help maintain healthy cardiovascular function and methylation pathways.*

    Cellular Energy*

    Active B12 and B6 help convert nutrients into cellular energy and promote overall vitality.*

    Active Forms, Ready to Use

    Liposomal Delivery

    Liposomal Delivery

    Liposomal delivery helps protect active B vitamins and support absorption so the body can use methylcobalamin, adenosylcobalamin, and P5P more efficiently.

    Third-Party Tested

    Third-Party Tested

    Tested for purity and quality by accredited third-party laboratories. Each batch is screened for microbial contaminants, heavy metals, and other specified contaminants.

    Made for Daily Energy

    Made for Daily Energy

    Taking B vitamins in their active forms helps ensure the body can use them directly to support healthy nervous system function, cellular health, and cardiovascular support.*

    Inside Liposomal Vitamin B12 + B6

    Vitamin B6 (P5P)

    Vitamin B6 (P5P)

    What it is:

    Pyridoxal-5-Phosphate (P5P) is the active coenzyme form of vitamin B6. It supports more than 100 enzymatic reactions in the body, including those involved in healthy neurotransmitter production and red blood cell formation.*

    Why we use it:

    Most supplements use B6 as pyridoxine hydrochloride, which requires conversion before the body can use it. P5P is already active, supporting serotonin, dopamine, and GABA production, along with hemoglobin synthesis.

    Vitamin B12 Methylcobalamin

    Vitamin B12 Methylcobalamin

    What it is:

    Methylcobalamin is one of the two active coenzyme forms of vitamin B12. It supports neurological health, DNA synthesis, and red blood cell formation.*

    Why we use it:

    Unlike synthetic cyanocobalamin, methylcobalamin is a bioactive form of vitamin B12 that the body can readily utilize. It helps support mood, memory, and energy production, while contributing to the health of the brain and nervous system.*

    L-Methylfolate

    L-Methylfolate

    What it is:

    L-methylfolate is the bioactive form of folate, a B-vitamin essential for methylation, DNA synthesis, and detoxification. The calcium component helps stabilize L-5-MTHF.

    Why we use it:

    Humans cannot synthesize folate and must obtain it through food or supplements. L-5-Methyltetrahydrofolate (L-methylfolate) bypasses conversion steps that can be reduced by MTHFR gene variations, supporting more consistent folate availability.*

    Vitamin B12 Adenosylcobalamin

    Vitamin B12 Adenosylcobalamin

    What it is:

    Adenosylcobalamin is the second active coenzyme form of Vitamin B12. It is stored in the mitochondria, where it drives energy production by supporting fatty acid and amino acid metabolism.

    Why we use it:

    Vitamin B12 must be converted into its active forms—methylcobalamin and adenosylcobalamin—in order to be utilized by the body. Using both active forms helps support brain, nerve, and heart health.*

    How to use

    How to use

    How

    Take one serving daily or as directed by your healthcare professional.

    When

    This formula can be taken any time of the day.

    Dose

    1 Packet.

    Notes

    Best taken in the morning.

    Got any questions?
    We have answers

    Why active forms of B vitamins?

    Taking B vitamins in their active forms helps ensure the body can use them directly to support healthy nervous system function, cellular health, and cardiovascular support contributing to overall wellness.*

    Who should take this product?

    Due to this product's cellular energy support, cardiovascular health support, and cognitive health support,* anyone can benefit from adding this to their routine. The formula is ideal for vegans and vegetarians who otherwise have no B12 in their diet.

    When should I take it?

    This product can be taken any time of day, but it is best enjoyed in the morning.

    Is this suitable for a vegan diet?

    Yes. B12 is one of the nutrients hardest to obtain from a plant-based diet, which makes a daily active-form B12 a common addition to a vegan routine.*

    *The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease.

    What clinicians are saying

    Clinicians can receive free samples

    Clinicians can form a hands-on opinion of this product.

    Never paid for a review

    Clinicians are not compensated for reviews.

    Collected by FrontrowMD

    A third-party platform — not Cymbiotika.

    Learn more

    3 reviews

    Verified Clinician

    JQ Dr. Jonathan Quinonez, DO

    Dr. Jonathan Quinonez, DO

    Internal Medicine, 9 Yrs Experience

    Targets dips in mental and physical energy with a B-vitamin blend

    It's easy to chalk up feelings of mental and physical sluggishness to a long day or a demanding week, but other factors like nutrition may be involved. When patients feel frustrated with their cognitive or physical performance, this liposomal B vitamin blend is one that comes to mind. While the liposomal aspect stands out to me, another key differentiator is that this blend has two forms of B12 that the body can use directly: methylcobalamin and adenosylcobalamin. That's encouraging because of the role B12 plays in helping the body turn nutrients from the food we eat into energy we can use. I like the idea of beginning the day with this blend. It's a way of working with the body's natural energy processes rather than relying on coffee or energy drinks.†

    • Replenishes stamina
    • Methylcobalamin source
    • Naturally energizing
    • Nutrients

    Verified Clinician

    RK Dr. Rathinam Krishnamoorthy, MD

    Dr. Rathinam Krishnamoorthy, MD

    Internal Medicine, 58 Yrs Experience

    Sharpens cognition with active forms of B12 and folate in a liposomal formula

    This Cymbiotika formula looks like a strong option to help adults maintain their concentration through the day. B vitamins, which are often linked with supporting focus and attention, are the key ingredient. What drew my attention to this Cymbiotika formula over other B vitamin blends is that it contains active forms of B12 and folate. The specific form of folate here, called calcium L-5-methyl-THF, has also been recognized for its favorable absorption properties. Building on the potential benefits of these ingredients, this formula contains liposomes. Liposomes are fat-based structures that may help protect the nutrients inside them from degradation. I find that beneficial for adults who are interested in supporting their cognitive function with a quality formula.†

    • Focused attention
    • Bioavailable folate
    • Liposomal protection
    • Nutrients

    Verified Clinician

    SC Sara Caracostas, NP

    Sara Caracostas, NP

    Family medicine, 4 Yrs Experience

    B vitamin support for energy production, the nervous system, and heart health

    I think patients interested in supplementing with B vitamins should start with Liposomal Vitamin B12+B6. I love that Cymbiotika has formulated this product's key nutrients, including P5P, methylfolate, and methylcobalamin, into a drinkable pouch. These forms may be easier for the body to put to use. A common thread between each of these nutrients is that they are all known to play important roles in the production of cellular energy. They may also contribute to the function of the cardiovascular and nervous systems, which are key for overall health and well-being. I can see this product serving well as a complement to whole food sources of B vitamins, like meat or dairy, or as targeted supplementation for vegans and vegetarians.†

    • B-vitamin drink
    • Energy production
    • Whole-body wellness
    • Nutrition Reviews

    †This clinician wants to clarify that larger-scale research to support their product claims is still developing. These statements have not been reviewed by the FDA and are not intended to be medical advice.

    COMMUNITY

    What others are saying

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    Three packets, one simple routine

    Three packets, one simple routine